2-Minute Neuroscience: Long-Term Depression (LTD)

[2:00]

Long-term depression, or LTD, is a process by which synaptic connections between neurons are weakened. Although the functions of LTD are not completely understood, it may be important to memory formation—perhaps by resetting previous synaptic changes to allow for new memories to be formed via long-term potentiation (LTP). In this video, I discuss the best understood mechanism underlying LTD, which involves AMPA and NMDA glutamate receptors.

[Video and text source: Neuroscientifically Challenged YouTube channel]