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2-Minute Neuroscience: Long-Term Potentiation (LTP)

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Long-term potentiation, or LTP, is a process by which connections between neurons become stronger with frequent activation. LTP is thought to be a way in which the brain changes in response to experience, and thus may be an mechanism underlying learning and memory. In this video, I discuss one type of LTP: NMDA-receptor dependent LTP. I outline the mechanism underlying NMDA-receptor LTP and describe how it is thought to strengthen synaptic connections where it occurs.

[Video and text source: Neuroscientifically Challenged YouTube channel]